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Agmatine is a chemical substance which is naturally created from the amino acid arginine. Agmatine has been shown to exert modulatory action at multiple molecular targets, notably :neurotransmitter system, ion channels, nitric oxide, synthesis and polyamine metabolism and this provide basis for further research into potential applications. Agmatine seems to help manage different chemicals and pathways in the brain. This might improve certain conditions of the brain and nervous system.